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Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate.

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Autotaxin (ATX). an autocrine motility factor that is highly upregulated in metastatic cancer. is a lysophospholipase D enzyme that produces the lipid second messenger lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Dysregulation of the lysolipid signaling pathway is central to the pathophysiology of numerous cancers. https://www.parisnaturalfoodes.shop/product-category/silver-sln/
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