Inflammatory pathology of the nasal cavity and paranasal sinuses is one of the major challenges in otorhinolaryngology today. Among patients hospitalized in ENT units. the incidence of inflammatory diseases of the paranasal sinuses is up to 36%. Modern macrolides (especially clarithromycin and azithromycin) are among the most common antibiotics in outpatient practice. https://www.foldlyers.shop/product-category/holders/