We have previously described genetic constructs and expression systems that enable facile production of recombinant derivatives of botulinum neurotoxins (BoNTs) that retain the structural and trafficking properties of wt BoNTs. In this report we describe the properties of one such derivative. BoNT/A ad. which was rendered atoxic by introducing two amino acid mutations to the light cha... https://hollandscountryclothinges.shop/product-category/horse-saddle-pads/